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Agenda
Day One: January 23, 2008
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8:00am
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Registration
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9:00am |
Protein Production, Engineering and Crystallization
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9:05am |
Combinatorial Engineering and Screening of Protein Libraries for Crystallography Applications
Joseph Kittle, Senior VP Research and Technology, Coda Genomics
Coda has developed novel, high throughput methods for selecting gene variants that produce soluble proteins for structure and function studies.
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9:35am |
Keynote Address - Dealing with the Bottleneck of Crystallization
Zygmunt Derewenda, Professor, University of Virginia
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10:20am
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Coffee and Networking in Exhibit Hall
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11:05am |
New Instrumentation and Large Scale Automation
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11:10am |
New Insights into Biomolecule Crystallization Process using Dynamic Light Scattering in Multi Plates
Christian Betzel, Professor, University of Hamburg
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11:40am |
Keynote Address - New Developments in High-throughput Crystallization: Automatic Execution of Follow Up Experiments
Jochen Muller-Dieckmann, Team Leader, EMBL
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12:25pm
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Lunch and Poster Viewing
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1:55pm |
Protein Crystallization for High-Throughput Structural Biology
George Phillips, Professor, University of Wisconsin - Madison
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2:25pm
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Coffee and Networking in Exhibit Hall
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3:10pm
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The PX Scanner: New Developments Enabling Complete Low Temperature Data Collection
James Duncan, Oxford Diffraction
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3:40pm |
Drinks Reception - Sponsorship Opportunities Still Available
Contact Ian.Slade@selectbiosciences.com |
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Day Two: January 24, 2008
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9:00am |
Advances in Diffraction Techniques and Crystallographic Computing
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9:05am |
New Developments on FIP-BM30A for Protein Crystallography Automation: From Accelerated Sample Transfer System to in situ Crystal Analysis
Lilian Jacquamet, Beamline Scientist, Institute de Biologie Structurale
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9:35am |
Keynote Address - Pipelining Ligands in PHENIX
Nigel Moriarty, Scientist, Lawrence Berkeley National Laboratory
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10:20am
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Coffee and Networking in Exhibit Hall
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11:05am
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Automation, Robotics and Remote Access at the SSRL Protein Crystallography Beam Lines
Clyde Smith, Staff Scientist, Stamford University
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11:35am |
Identification of Macromolecular Assemblies in Crystalline State
Eugene Krissinel, Researcher, European Bioinformatics Institute
A method is presented for the identification of macromolecular assemblies in crystal packing, based on chemical stability analysis by estimating free Gibbs energy of assembly dissociation. The method implementation is publicly available as an interactive web-server.
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12:05pm
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Lunch and Poster Viewing
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1:35pm |
New Drug Target Structures and Analysis Tools
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1:40pm |
Crystallographic Investigations on Insulin: Discovery and Development Applications
Gerd Schluckebier, Principal Scientist, Novo Nordisk A/S
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2:10pm |
Keynote Address - Targeting Resistant and Persistent M. Tuberculosis
James Sacchettini, Professor, Texas A&M University
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2:55pm |
Pharmacophore Modeling and Virtual Screening to Identify Novel Bio-active Molecules
Gerhard Wolber, Executive Partner, Inte:Ligand GmbH
- How to use structure-based pharmacophore screening as an alternative to high-throughput docking - Advantages through in-silico activity profiling - Early risk assessment and efficient hit prioritization by using 3D pharmacophores
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3:25pm |
Crystallography in Iterative Lead Discovery and Optimization
Shankari Mylvaganam, VP of Research, Sapient Discovery
In this presentation we will present case histories wherein crystallography has played a major role in lead discvovery and optimization. In particular we will point out that high-throughput crystallography may not always be ideal for real time drug discovery.
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3:55pm |
Coffee and Close of Conference |
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