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Provisional Agenda
Day 1 - 7th May 2008
| 08:00 |
Registration |
| 09:00 |
PCR and Non PCR-based Detection Techniques
Session Chair: Thanos Mitrelias, Cambridge University |
| 09:05 |
Development of a Real-Time One-Step Reverse Transcriptase PCR for quantitation of Chandipura Virus RNA and comparison with in-vivo in-ovo and in-vitro quantitation assays
Satyendra Kumar, Senior Research Fellow, National Institute of Virology
This study reports development of a real time one step RT-PCR assay for the quantitation of CHPV. This system is highly sensitive. The assay was found reproducible at both high and low viral loads. Considering rapid course of Chandipura encephalitis in children and high mortality, we assessed usefulness of real time one-step PCR assay in diagnosis. |
| 09:35 |
Rapid Biosensing using Magnetic Nanoparticles
Andre Immink, Principal System Architect, Philips Corporate Technologies
This talk focuses on a novel biosensor technology based on superparamagnetic nanoparticles as labels. The use of such nanoparticles enables fast single-step assay formats without any fluid wash steps, detection in raw samples, and integration into a miniaturized system. The detection technology will be described as well as biological performances for a range of biological assays (competition immunoassays, sandwich immunoassays, and DNA assays). |
| 10:05 |
Coffee & Networking in the Exhibition Hall |
| 10:50 |
Encoding High Throughput Suspension-based Biotechnology Assays Using Digital Planar Magnetic Microtags
Thanos Mitrelias, Visiting Scientist, Cambridge University
The development of a Method for in Situ Encoding chemical libraries prepared by split and mix method, using planar magnetic tags and comprising a vast number of probes. |
| 11:20 |
Liquid Crystal-Mediated Bioassay for Small Peptide and Protein Detection
Kun-Lin Yang, Assistant Professor, University of Singapore
Liquid crystal based bioassay provides a new means of detecting peptides and proteins in a label-free manner. |
| 11:50 |
On-the-flow pathogen characterization based on native fluorescence detection
Peter Kiesel, Senior Scientist, Palo Alto Research Center
Native fluorescence spectroscopy is promising for pathogen detection since it is sensitive and requires neither specific binding nor tagging. Our compact detection platform combines fluidic channels with chip-size spectrometers and records fluorescence from analytes as they traverse the channel.
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| 12:20 |
Lunch & Poster Viewing |
| 14:00 |
Combining Microfluidics, Microlables, and Magnetoelectronics for Attomolar Biosensing
Cy Tamanaha, Research Engineer, Naval Research Laboratory
This presentation will describe a unique technology that combines microfluidics, magnetic microlables, and magnetoelectronics for attomolar biosensing. Components to be covered include our Fluidic Force Discrimintation™ assay method, and our automated magnetoelectronic biosensor system prototype, cBASS® |
| 14:30 |
Advanced Applications of xMAP Technology for Pathogen Detection Using a Chip-Scale Implementation of Bead-Based Flow Cytometry
Adam Schilffarth, Vice President, Research & Development Luminex Corporation
This presentation will discuss a chip-scale implementation of a bead-based flow cytometry bio-detection technology suitable for a variety of applications including medical diagnostics, drug discovery, and environmental pathogen sensors. This new concept involves an optimized implementation of micro-fluidics, electronics, and photonic components designed to provide very high performance, compact form-factor, and greatly reduced cost compared to current generation systems. |
| 15:00 |
Coffee & Networking in Exhibition Hall |
| 15:45 |
Generation and Use of Mammalian Cell-based Detection Methods
Bart Van den Burg, BioDetection Systems B.V.
Mammalian cell-based detection methods to detect toxic substances. |
| 16:15 |
International Biorisk Management Standard
Strengthening a Global Biosafety/Biosecurity Framework
Ursula Jenal, Jenal & Partners Biosafety Consulting
The development of an international biorisk management standard is one of the main international projects to strengthen the implementation and harmonization of Biosafety and Biosecurity manage-ment necessary to protect the global community and the environment from the use and possible mis-use of biological agents and to give guidance for the safe handling of micro-organisms and their products within laboratory settings. The biorisk management standard will provide stakeholders with a benchmark for setting biosafety/biosecurity standards for facilities and will serve as a basis to enhance the safe international exchange and collaboration involving biological agents. |
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16:45 |
TIRF-EC Biosensors - Dynamic DNA and Protein Microarrays for Accurate and Rapid Detection of Pathogens
Alexander Asanov, President, TIRF Technologies
This presentation will describe portable and handheld biosensors based on novel technology, which combines Total Internal Reflection Fluorescence (TIRF) and ElectroChemistry (TIRF-EC). In conjunction with reagentless assays that require minimum sample preparation stages, TIRF-EC sensors rapidly and sensitively detect nucleic acid and protein signatures of pathogens. Due to high multiplicity of detection the probability of false positive responses is negligibly small. |
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17:15 |
Genome Identification Universal System (GENIUS)
John Jakupciak, Cipher Systems
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17:45 |
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18:15 |
Drinks Reception |
Day 2 - 8th May 2008
| 08:55 |
Point of Care Pathogen Detection
Session Chair: Thanos Mitrelias, Cambridge University |
| 09:00 |
Development of Point of Care Test for Accurate, Rapid Diagnosis of Active TB
Robyn Lindner, Head of Discovery, Proteome Systems Ltd
Proteome Systems is developing an improved test for TB. The target: Cost effective, antigen based, point-of-care test for active TB via pipeline test development from biomarker discovery to test development. |
| 09:30 |
Emerging Pathogens and Pathogen Biomarkers - Anthrax
Amit Banerjee, Assistant Professor, Wayne State University
Anthrax Lethal Factor (LF) is a metalloprotease that inactivates key signaling molecules, such as MAPKK, to ultimately cause cell death. Inhibition of this Anthrax-LF toxemia is absolutely necessary to provide therapeutic significance, combined with antibiotics during and also immediately after an Anthrax infection. High throughput in silico drug screening is being used for finding and developing hitherto unavailable small molecules to block the function of Anthrax LF by interfering with its catalytic mechanism. |
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10:00 |
Sequence-Enabled Reassembly (SEER) for the detection of genetic information
David Segal, Assistant Professor, University of California
Sequence-enabled reassembly (SEER) is a novel methodology to detect the presence of specific genetic and epigenetic information directly from samples of double-stranded DNA. It should have advantages in live cells, field kits, and point-of-care detection. |
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10:30 |
Coffee & Networking in the Exhibition Hall |
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11:25 |
A rapid high-throughput method for the detection of K-ras gene single-nucleotide polymorphism based on tag-array
Dr Dang Bang, Post Doctorial Associate, University of Denmark
A robust tag-array-based hybridization system was developed for the detection of the K-ras gene single-nucleotide polymorphism (SNP). It is a useful method for early and large-scale detection of colorectal cancer (CRC). |
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11:55 |
Genomic Barcoding for Biothreat Countermeasure Implementation
Dr Willy Valdivia, CEO, Orion Integrated Biosciences Inc.
A New Approach for Targeted Detection, Diagnostics and Surveilliance Development. |
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12:25 |
Lunch & Poster Viewing |
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14:00 |
Effects of the Complex Backgrounds on the Quality of Pathogen Detection
Dr Yuriy Fofanov, Associate Professor, University of Houston |
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14:30 |
Close of Conference |
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