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Day 1 - Tuesday 24th August 2010

08:00

Registration

 

Session: Current Trends in Cellular Therapy

09:30

Control of Paracrine, Autocrine and Intracrine Myocardial Signals: An Emerging Cell Therapy Strategy in Cardiovascular Diseases
Carlo Ventura
, Professor, National Institute of Biostructures and Biosystems, University of Bologna Italy
Autocrine, paracrine and intracrine mechanisms may establish a multidirectional crosstalk between cardiomyocytes, non-cardiac cells, endogenous or exogenously administered stem cells. This cardiac building block unit might be used as a tool for re-interpreting the cell therapy of failing heart.

10:00

Keynote Presentation
Stemming Vision Loss Using Stem Cells – Seeing Is Believing
Peter Coffey
, Professor, University College London
The London Project to Cure Blindness aims to make the most of human embryonic stem cells to prevent blindness and restore sight in patients with Age-related Macular Degeneration (AMD) by 2012.

10:30

Coffee and Networking in Exhibition Hall

11:15

Stem Cell Therapy for Blinding Ocular Surface Diseases
Julie Daniels
, Lecturer, University College London
The challenges of producing a cost effective and reproducible stem cell based therapy for the treatment of blinding ocular surface disease will be discussed.

 

Session: CNS Disease Cellular Therapy

11:45

Development of Functional Human Dopaminergic Nuerons from Ventral Mesencephalic Nueral Stem Cells, in vitro and in vivo
Alberto Martinez-Serrano
, Associate Professor, Autonomous University of Madrid
Human neural stem cells from the ventral mesencephalon retain their regional identity in culture, and develop into functional dopaminergic neurons both in vitro and after transplantation into the 6-OH-DA lesioned rat. Gene expression, synaptic vesicle dynamics, functional transport, calcium imaging, electrophysiology, in vivo behaviour amelioration, and functional imaging evidence.

12:15

Tech Spotlight



Cellular Therapeutics: The Path Towards Commercialization
Christian van den Bos, Executive Programme Manager, Lonza

12:30

Lunch and Networking in Exhibition Hall

13:30

Poster Session

14:15

Cell Replacement and Integration in the Cerebellar Circuitry
Ferdinando Rossi
, Professor University of Turin
The presentation will review recent experiments aimed at elucidating cell-environment interactions that direct the specification, differentiation and integration of new neurons in the cerebellar circuitry.

14:45

Engineering Stem Cells for Neural Repair by Direct Delivery of Recombinant Proteins
Frank Edenhofer
, Professor, University of Bonn - Medical Centre
Stem cells have become a major focus of scientific interest as a potential source of transplantable cells for regenerative medicine. This paper describes direct intracellular delivery of transcription factors as alternative modality to control lineage differentiation in stem cell cultures without genetic modification.

15:15

Coffee and Networking in Exhibition Hall

Session: Musculoskeletal Disease Cellular Therapy

16:00

Novel Stem Cell-based Approaches to Joint Tissue Repair
Cosimo De Bari
, Professor, University of Aberdeen

16:30

Clinical Use of Stem Cell Regenerative Therapy in Patients with Severe Bone Disorders and Wound Healing
Manzoor Mangi
, Director, Stemcellfix Biomimetic Therapy
Currently there is a great deal of interest in biologic cell therapy for wound and fracture healing. Orthopaedic injuries and non-healing fractures cases continue to grow and various synthetic bone-graft substitutes and biologic MSC are used for optimal bone regeneration. In this presentation the role of adult Bone marrow derived stem cells and human multipotent adipose-derived stem cells will be highlighted for clinical purposes.

17:00

Derivation of Endothelial Cells from Stem Cells and Functional Assessment in vitro and in vivo
Andrew Baker
, Professor, Glasgow University
Vascular endothelial cells are an important target cell population for regenerative medicine in cardiovascular complications. Our research has focused on the development of efficient and translatable protocols for the derivation of functional endothelial cells from human embryonic stem cells.

Session: Tissue Engineering and Emerging Themes

17:30

Expanding Primary Cells
Tobias May
, Scientist, Helmholtz Centre for Infection Research
We developed a cell expansion system facilitating strict control of proliferation. The system is flexible and regulation is easily achieved. Most importantly, it generates an unlimited number of cells with an in vivo like physiology.

18:00

Drinks Reception / End of Day 1

Day 2 - Wednesday 25th August 2010

09:00

Bioreactor Culture of ES Cells
Christopher Ward
, Professor, Manchester University
The use of E-cadherin antagonists for the culture of embryonic stem cells in single cell suspension will be discussed in this presentation.

10:00

Tissue Engineering of the Kidney: Working With the Grain of Adaptive Self-Organization
Jamie Davis
, Professor, Edinburgh University
The presentation describes progress towards the aim of making new kidneys from human stem cells, for the purposes of regenerative medicine.

10:30

Coffee and Networking in Exhibition Hall

11:15

The Automation of Human Stem Cell Culture
David Williams
, Professor, Loughborough University
This presentation will describe work at Loughborough to automate human stem cell culture for both research and clinical use in collaboration with The Automation Partnership, Nottingham University and others.

11:45

Title to be Confirmed

12:15

Lunch and Networking in Exhibition Hall

13:30

Poster Session    

14:00

PDP Cells Can Regenerate Critically Damaged Adult Pancreatic Tissue and Completely Reverse Streptozotocin Induced Diabetes
Paul Shiels
, Senior Lecturer in Transplantation, University of Glasgow
A novel adult cell type from humans and rat can stimulate host tissue to completely regenerate in a mouse model of diabetes.

14:30

The Evolution of Pluripotency and Germ Cell Specification
Andrew Johnson
, Professor, Nottingham University
How pluripotency evolved is unknown because it is not conserved in Xenopus or zebrafish. We demonstrate pluripotency in axolotl embryos, and show it is under the control of a conserved Nanog ortholog that can govern pluripotency in ES cells.

15:00

Coffee and Networking in Exhibition Hall

15:30

Engineering Adipose Mesenchymal Stromal Cells for Cancer Therapy
Massimo Dominici
, Assistant Professor, University Hospital of Modena and Reggio Emilia
This presentation will rapidly review MSC-based cancer therapies presenting novel data on the use of gene modified adipose derived MSC capable to dramatically induce cancer death.

16:00

Close of Conference