These courses are being held in parallel with the Ion Channel Targets conference.
Register for either, or both, courses and you will automatically receive a full delegate pass to the conference. This includes access to all sessions, the exhibition and refreshments during the event (regular price $999).
Fluorescence Assays in Drug Discovery
All day 8 September and morning of
9 September 2008
Fluorescence Assays in Drug Discovery will commence at 8:30am for registration and coffee and will finish at 5:00pm on 8 September, recommencing on 9 September at 9:00am and finishing at 12:30pm.
What will I gain by attending ?
- Master the basic concepts of fluorescence at the level required to understand fluorometric assays and instrumentation.
- Become familiar with the application of fluorometric assays to the major classes of pharmacological targets.
- Understand the basis and applications of advanced methods such as fluorescence imaging, fluorescence polarization, time-resolved energy transfer, and fluorescence-fluctuation spectroscopy.
- Learn the important types of interferences in fluorometric assays.
- Discover where to find more advanced information, using the extensive list of references provided.
Fluorescence course topics:
-
Fluorescence fundamentals
- Labels and labeling chemistries
- Instrumentation
- Interferences and limitations
- Survey of principal fluorescence methods
- Biochemical and cellular applications
Enzyme & Binding Assays in Drug Discovery
Afternoon of 9 September and all day
10 September 2008
Enzyme & Binding Assays in Drug Discovery will commence at 1:00pm on 9 September for registration and coffee, and will finish at 5:00pm, recommencing on 10 September at 9:00am and finishing at 5:00pm.
What will I gain by attending ?
- Master the basic concepts underlying enzyme and binding assays
- Learn how applications in drug discovery sometimes dictate assay optimization and interpretation which differ from textbook recommendations
- Learn how best to extract the information you need from your assays
Enzyme & Binding course topics:
- Enzyme kinetics
- Enzyme inhibition: Competitive, noncompetitive, uncompetitive, irreversible, and promiscuous
- Multiple-substrate enzymes
- Binding equilibria and kinetics
- Deviations from classical textbook behavior
- Optimizing enzyme and binding assays for primary vs. secondary screening
- Understanding mechanisms and extracting information from your data
- Discussion of commercial data-analysis and simulation software
- Case studies, including receptor binding, kinases, and proteases