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Advances in Docking and Structure Based Compound
Screening (audio files only)
Ruben Abagyan, Professor, Department of Molecular Biology, Scripps Research Institute
Unveiling Drug Selectivity Via Functional Profiling
and a Multi-Prong Approach to Hit Validation Using Chemiscreen™ GPCR Cell Lines
Blaine N. Armbruster, Product Manager - GPCR Drug Discovery, Millipore
Point-of-Care Diagnosis Through Impedimetric Detection of a Biomarker in Whole Blood
Vincent Auger, Research Fellow and Coordinator of the European DVT-IMP Project, University of Teesside
New Approaches to the Discovery of Novel Chemical Reactions and Chemotypes
Aaron Beeler, Assistant Director, Centre for Chemical Methodology and Library Development, Boston University
Phenotypic Cell-Based Assay Development for HTS for Anti- Infectious Diseases Drugs Identification
Thierry Christophe, Head of Screening Technologies and Pharmacology, Pasteur Institute Korea
Analogs of Griseofulvin with Enhanced Anticancer Activity
Mads Clausen, Assistant Professor, Technical University of Denmark
Time Dependent Cytochrome P450 Inhibition: Review of the Common Sub-Structures and Implications for Drug Development
Patrick Dansette, Research Director and Head of the Cytochrome P450 team, CNRS UMR8601
A Dominant Role for Transporters in Xenobiotic Uptake?
Paul Dobson, Cheminformatics Research Associate, Manchester Interdisciplinary Biocentre, University of Manchester
High Content Screening of Human ES Cells Using Laser
Scanning Confocal Microscopy
Hakim Djaballah, Director, Memorial Sloan Kettering Cancer Centre
ConGO: A New Paradigm for Pattern Recognition of Drug Electronic Structure
Maria Grishina, Associate Professor, Chelyabinsk State University
Clinical Pharmacokinetic and Toxic Consequences of the Induction of Transporters and Drug Metabolising Enzymes
Nicola Hewitt, Scientific Consultant, SWS/DMPKORE
Adult Epithelial Stem Cell Assay Development
Patricia Hurley, Principal Scientist, Novel Therapies Division, Epistem Holdings
Applications of an ADME Knowledge Database for Predictive Models and Drug-Drug Interactions Assessment
Ismail Ijjaali, Application Scientist, Aureus Pharma
Slide-Based Miniaturized Microtiter Plate for ELISA and Cellbased Assays
Namyong Kim, Team Leader and Senior Research Scientist, Institute of Bioengineering and Nanotechnology
High-Throughput siRNA Transfection Applying a 384-Multichannel Pipetting Head Avoiding Disposable Tips
Eberhard Krauß, Head, HT-Technology Development Studio, Max
Planck Institute of Molecular Cell Biology & Genetics
Effector-Dependent Signaling Profiles of GPCR Ligands in
Recombinant and Primary Cells
Evi Kostenis, Head of Department, Director of Institute, University of Bonn
Rescuing ADME Properties - Prodrugs and Other Tricks
Hugo Kubinyi, Retired Professor, University of Heidelberg
Synthesis of Pharmacologically Relevant Ring Systems by One-Pot Cyclizations
Peter Langer, Professor, Institute for Chemistry, Department of Organic Chemistry, University of Rostock
Efficient Assembly and Selection of Macrocycle Libraries by DNA-Programmed Chemistry
Jinbo Lee, Head of Chemistry, Ensemble Discovery Corporation
Using 3-D Culture Models to Screen for Compounds that
Induce Apoptosis of Cancer Cells
Stig Linder, Professor, Group Leader, Karolinska Institute
In silico ADMET Traffic Lights and PhysChem Scores and Their Application to Kinase Inhibitors
Mario Lobell, Computational Chemist, Bayer HealthCare
Multi-Component and Domino Syntheses of Pharmaceutically Relevant Heterocycles
Thomas Müller, Professor, Chair of Organic Chemistry, Heinrich-Heine-University Düsseldorf
Cell-Impedance Measurements of GPCR Modulators –
Characterization of Signalling Pathways in Non-Recombinant
Cells
Oliver Nayler, Director, Head Molecular Biology, Actelion Pharmaceuticals
A Flexible HCA System for the Automatic Image Analysis and Interpretation of Cell Images
Petra Perner, Director, Institute of Computer Vision and Applied Computer Sciences, IBaI
Multiplexing ADME-Tox Cell-Based Assays Using Primary Cells
Terry L. Riss, Director of Project Management, Promega Corporation
Improving Processes in Lead Optimisation
Andreas Sewing, Research Fellow/Director, Pfizer
qPCR and Methylation Sensitive qPCR Performance at Sites of
Stable non-B DNA Structure in Human Gene Promoters
Steven Smith, Professor of Molecular Science, City of Hope
Molecular Effects of Akt and Src on the Activity of mTORDependent Signalling Pathway in v-Src-Transformed Cells
Zdena Tuhackova, Senior Researcher, Institute of Molecular Genetics, Academy of Sciences of Czech Republic
Structure Based Design of a Novel and Highly Potent Anti-HIV Non-Nucleosidic-Reverse-Transcriptase-Inhibitor: IDX12899
Christophe Parsy, Associate Director, Idenix Pharmaceuticals
Functional Characterization of GPCR in the Light of Evolution
Torsten Schöneberg, Professor of Molecular Biochemistry and
Endocrinology, Institute of Biochemistry, Medical Faculty, University of Leipzig
Identification of Therapeutic Targets Associated with PI3K/Akt Signalling Through High Content Loss-of-Function Screenings
Fábian Zanella de Sá, PhD Student, Assay Development Group, Experimental
A Method for Label-Free Screening in Fragment-Based Drug Design
Andrei Zhukov, Development Scientist, GE Healthcare Bio-Sciences
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