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 Purchase CD >> Screening Targets
A Phenotypic-based Approach for Identification of off Target Effects and Mechanism of Drug Action
Yama Abassi, Director, ACEA Biosciences
A Cell-based Assay for IkBa Stabilization Using a Two-Color Dual Luciferase-Based Sensor
Eric Davis, Metabolism Branch, National Cancer Institute
Automated Patch Clamp for High-quality, Versatile Ion Channel Screening
Cecilia Farre, Senior Scientist, Nanion Technology
The CellKeyTMSystem: A Biorelevant Cell Based Assay Platform and its Application for Secondary Screening of GPCRs
Debra Gallant, Applications Scientist, MDS Sciex
Addressing the Challenges to GPCR Screening
Annette Gilchrist, CSO, Caden Biosciences
A Novel, Label Free Analysis Tool for Screening Transporter Proteins
Carsten Haber, Scientist, IonGate Biosciences
Hsp90 Inhibition for Cancer Therapy
Rob Howes, Senior Team Leader, Vernalis
Use of Novel High-content Assays to Identify New Treatments for Huntington’s Disease
Stefan Jaeger, Evotec
Light Induced Depolarization of Cells: An Emerging Tool for HTS of Voltage-Dated Ion Channels
Bela Kelety, Director R&D, IonGate Biosciences
Interrogating Diverse Target Families by Homogenous Immunodetection of Nucleotides
Robert Lowery, President and CEO, Bell Brook Labs
Flash Luminescence in HTS
Andrea Rossignoli, Senior Scientist, Axxam
Ion Channel Targets
Actual vs. Assumed Compound Concentration in Ion Channel Screening: Issues and Solutions
Arnon Chait, President, Analiza
Pharmacological Modulation of Ca2+ Sensitivity of Small Conductance Ca2+ - Activated K+ Channels: A Challenge in Drug Discovery
Palle Christophersen, Director – Electrophysiology, Neurosearch
Development of Cellular Tools for High-throughput Screening of Voltage-Gated Sodium Channels
Colin Dick, Ion Channel Products Manager, Scottish Biomedical
The Voltage-gated Sodium Channel Nav1.7 in Analgesia: Target Validity and Screening Strategies
Johannes Krupp, Section Head – Lead Discovery Biology, AstraZeneca
Chiptips®, A Breakthrough in Automated Patch Clamp
Albrecht Lepple-Weinhues, flyion GmbH
A Comprehensive Cardio Safety Strategy – With the Impact by Emerging Technologies
Qiang Lu, Head – Ion Channel and Cellular Toxicology, Novartis
Utilizing Automated Electrophysiology to Develop Ligand-Gated Ion Channel Profiling Assays for Drug Discovery
Jonathan Mann, Research Scientist, Millipore
Validation of the CRAC Channel as a Potential Target for T Cell-Mediated Immune Diseases
Martin Mense, Scientist II, Synta Pharmaceuticals
Evaluation Ion Channel Mechanisms in Murine Neuronal Cultures and Human Embryonic Stem Cell-derived Neurons Using FLIPR and Flex Station
Thomas Murray, Professor and Chair, Creighton University Medical School
Nicotinic Acetylcholine Receptors: Roles in Disease and as Drug/Chemical Targets
David Sattelle, Professor, University of Oxford
LOPAC Screen for Neurotransmitter Transporter Uptake Activity Using a Fluorescence-Based, Homogenous Assay
Richard Sportsman, VP – Reagents and Assays, Molecular Devices
PAP-1, A Small Molecule Kv1.3 Blocker, for the Treatment of Effector Memory T-Cell Mediated Autoimmune Diseases
Heike Wulff, Assistant Professor, University of California – Davis
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