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SELECTBIO Conferences Exosomes & Liquid Biopsies Europe 2018

Abstract



Stem Cell-Derived Extracellular Vesicles (EVs) as Therapeutics For Extending Healthspan

Paul Robbins, Professor of Molecular Medicine, The Scripps Research Institute

A universal characteristic of aging is loss of tissue regenerative potential due to stem cell dysfunction, contributing to the dramatic increase in the risk of morbidity and mortality. We have used both naturally aged mice and mouse models of accelerated aging to demonstrate that transplantation of young, functional adult stem cells results in an extension of healthspan. In addition, we have demonstrated that stem cell-derived EVs are a key factor for conferring the observed extension of healthspan by young stem cells. Progress towards developing clinically-relevant approaches using stem cell-derived extracellular vesicles to age-related pathologies will be presented. In addition, progress towards using circulating EVs as biomarkers of biological age will be presented.


Add to Calendar ▼2018-10-24 00:00:002018-10-26 00:00:00Europe/LondonExosomes and Liquid Biopsies Europe 2018Exosomes and Liquid Biopsies Europe 2018 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com