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SELECTBIO Conferences 3D-Printing in the Life Sciences

Luiz Bertassoni's Biography

Luiz Bertassoni, Associate Professor, Biomaterials and Biomechanics, School of Dentistry, Cancer Early Detection Advanced Research, Knight Cancer Institute, Oregon Health & Sciences University

Dr. Luiz Bertassoni obtained a PhD in Biomaterials from University of Sydney, and two postdoctoral degrees in Bioengineering from University of California San Francisco, and the Division of Health Sciences and Technology at Harvard Medical School and MIT. Currently, Dr. Bertassoni is an Associate Professor at Oregon Health and Science University (OHSU). He holds appointments at the Department of Restorative Dentistry, the OHSU Center for Regenerative Medicine, the Department of Biomedical Engineering and the Cancer Early Detection Advanced Research center (CEDAR) at the Knight Cancer Institute. Dr. Bertassoni’s encompasses various aspects of micro-scale technologies and bioprinting for tissue regeneration; nanoscale structural and mechanical properties of mineralized tissues; and different aspects in the field of ‘organs-on-a-chip’. His research has appeared in journals such as Nature Communications, Advanced Materials, Biofabrication, Lab on a Chip and others. Luiz has published over 45 manuscripts, including research articles, reviews and book chapters, and is a recipient of 28 national and international awards. He also serves as a reviewer for over 50 international peer-reviewed journals and an editorial board member of 5 journals.

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Nano to Microscale Engineering and Bioprinting of Vascularized and Innervated Bone-Like Microenvironments

Tuesday, 15 October 2019 at 16:00

Add to Calendar ▼2019-10-15 16:00:002019-10-15 17:00:00Europe/LondonNano to Microscale Engineering and Bioprinting of Vascularized and Innervated Bone-Like Microenvironments3D-Printing in the Life Sciences in Coronado Island, CaliforniaCoronado Island,

Bone tissue, by definition, is an organic-inorganic nanocomposite, where metabolically active cells are embedded three-dimensionally within a matrix material that is heavily calcified on the nanoscale. While the field of cell biology has evolved to culture cells three-dimensionally embedded in soft hydrogels, currently there are no strategies that replicate these definitive characteristics of bone tissue. Here, we describe a series of biomimetic approaches to mimic the 3D microenvironment of human bone. We discuss recently reported methods that we developed to encapsulate stem cells, vascular capillaries and nerve fibers within high density nanoscale mineralized materials that are inherently osteogenic. We also discuss digital light processing bioprinting strategies to mimic the structure, composition and function of the bone matrix. Ultimately, these approaches enable fabrication of bone-like tissue models with high levels of biomimicry with broad implications for disease modeling, drug discovery, and regenerative engineering.

Add to Calendar ▼2019-10-14 00:00:002019-10-15 00:00:00Europe/London3D-Printing in the Life Sciences3D-Printing in the Life Sciences in Coronado Island, CaliforniaCoronado Island,