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SELECTBIO Conferences Organoids & Microphysiological Systems 2022

Dong Pyo Kim's Biography

Dong Pyo Kim, Yonsan Chaired Professor, Pohang University of Science And Technology (POSTECH)

Professor Dong-Pyo Kim has extensive general experience and more than 25 year track record in synthetic and physical organic chemistry, process intensification using microreactors and flow chemistry/microreaction technology, communicated in ~300 scientific publications (h-index 52, citation 8,133). For the past decade the focus of his research has been directed towards flow chemistry using microreactor, encompassing a wide variety of synthetic transformations and experimental techniques. His research group is actively involved in projects dealing with API synthesis and sustainable manufacturing, employing a number of different enabling and process intensification technology.

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Microfluidic Encapsulation of Therapeutic Agents in Microdroplets and Nanoparticles

Wednesday, 14 December 2022 at 08:00

Add to Calendar ▼2022-12-14 08:00:002022-12-14 09:00:00Europe/LondonMicrofluidic Encapsulation of Therapeutic Agents in Microdroplets and NanoparticlesOrganoids and Microphysiological Systems 2022 in Long Beach, CaliforniaLong Beach,

Microdroplets (µ-droplet) and nanoparticles (NPs) have been attracted significant interest in the past decades to address different drug delivery challenges, including poor bioavailability, poor drug solubility, and lack of targeted delivery. Traditionally, µ-droplet and NPs are often produced using bulk methods. In comparison, microfluidics offers a new strategy for making µ-droplet and NPs with controlled shape and homogeneous size due to rapid mass transfer and precise control over reaction conditions. Herein, we present a continuous-flow method for effectively encapsulating various therapeutic agents (enzymes, chelators, magnetic nanoparticles, bio-imaging agents, etc.) into uniform size of polymeric µ-droplet and inorganic NPs by microfluidics. Furthermore, we controlled the mixing time between the reactants of carrier and the therapeutic agent by forming various flow patterns (chaotic, multiple-laminar flow) and developed a drug delivery system with an improved therapeutic effect through flow control. This work will contribute effective encapsulation of therapeutic agents in µ-droplet and NPs, which would be extended to biomedical applications.

Add to Calendar ▼2022-12-12 00:00:002022-12-14 00:00:00Europe/LondonOrganoids and Microphysiological Systems 2022Organoids and Microphysiological Systems 2022 in Long Beach, CaliforniaLong Beach,