Organoids with Reversed Biopolarity (ORBs): SARS-CoV-2 Drug Testing and Breast Cancer ProgressionTuesday, 19 November 2024 at 13:30 Add to Calendar ▼2024-11-19 20:30:002024-11-19 21:30:00Europe/LondonIntroduction to Microfluidics Training CourseOrganoids, Spheroids and Organs-on-Chips 2024 in Laguna Hills, CaliforniaLaguna Hills, CaliforniaSELECTBIOenquiries@selectbiosciences.com This presentation will describe production of sub-millimeter diameter, consistent size and shape, lung, kidney, and mammary organoids that have an inverted, apical-out geometry. These Organoids with Reversed Biopolarity (ORBs) are used in 384 well plates in a single-organoid-per-well format to test drugs and disease physiology. The airway ORBs are infected with high yields with multiple SARS-CoV-2 strains with Omicron variant showing highest viral replication and Delta giving the most inflammatory response. The ORBs also predict anti-viral drug efficacy correctly where conventional 2D cultures give false signals. Early-stage breast cancer progression model studies will also be discussed. Introduction to Microfluidics Training CourseTuesday, 19 November 2024 at 20:30 Add to Calendar ▼2024-11-19 20:30:002024-11-19 21:30:00Europe/LondonIntroduction to Microfluidics Training CourseOrganoids, Spheroids and Organs-on-Chips 2024 in Laguna Hills, CaliforniaLaguna Hills, CaliforniaSELECTBIOenquiries@selectbiosciences.com Course Runs from 20:30-22:30 Venue: Slate Room [Separate Registration Required to Attend this Training Course] |