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SELECTBIO Conferences Exosomes & Liquid Biopsies Europe 2018

Alison Devonshire's Biography



Alison Devonshire, Science Leader, LGC Limited

Following undergraduate degree, I worked as a clinical research associate implementing Phase II and III trials, before studying for my PhD in the transcriptional regulation of genes involved in metabolic diseases at the University of Surrey. For the last 10 years, I have worked in the Molecular and Cell Biology group at LGC, which holds the role of UK National Measurement Laboratory and Designated Institute for chemical and bio-measurements. I specialize in the application of nucleic acid measurements in clinical diagnostics and cellular analysis and am currently working on projects developing single cell-based approaches and standardizing measurements of cancer biomarkers.

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Approaches For Validation of Liquid Biopsy Testing of Circulating Tumour DNA

Thursday, 25 October 2018 at 16:15

Add to Calendar ▼2018-10-25 16:15:002018-10-25 17:15:00Europe/LondonApproaches For Validation of Liquid Biopsy Testing of Circulating Tumour DNAExosomes and Liquid Biopsies Europe 2018 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com

The typically low concentration of ctDNA in cancer patients’ samples makes validation of analytical sensitivity a critical element in the assessment of a diagnostic test. The potential for real-time monitoring of tumor dynamics through liquid biopsy testing also necessitates a systematic evaluation of quantitative accuracy.  This presentation will discuss approaches to validate the performance of targeted methods for cancer mutations, including pre-analytical controls, and the development of reference materials and reference measurement procedures, which also support longer-term comparability and standardization of patient testing.


Add to Calendar ▼2018-10-24 00:00:002018-10-26 00:00:00Europe/LondonExosomes and Liquid Biopsies Europe 2018Exosomes and Liquid Biopsies Europe 2018 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com