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SELECTBIO Conferences Exosomes & Liquid Biopsies Europe 2018

Takahiro Ochiya's Biography

Takahiro Ochiya, Chief, National Cancer Center Research Institute Japan

Dr. Ochiya carried a councilor of Japanese Cancer Association. After he got Ph.D. in 1988 in Osaka University and then went to do a post-doc at La Jolla Cancer Research (SF Burnham Institute for Medical Research), CA, USA. Dr. Ochiya’s lab focuses the development of novel animal models, methods, and strategies to study cancer development and metastasis. Especially, current focuses are siRNA- and microRNA-based therapy and exosome-mediated tumor metastasis. Dr. Ochiya has authored more than 260 peer-reviewed publications including 40 review articles, holds 24 Japan and 12 U.S. & Europe patents, and contributed to several books on stem cells, Extracellular vesicles, and RNAi medicine. Dr. Ochiya is a chief scientist of current Japan project of the Development of Diagnostic Technology for Detection of miRNA in Body Fluids (supported by NEDO/AMED).

Takahiro Ochiya Image

Early Detection of Cancer by Serum Exosomes

Wednesday, 24 October 2018 at 14:00

Add to Calendar ▼2018-10-24 14:00:002018-10-24 15:00:00Europe/LondonEarly Detection of Cancer by Serum ExosomesExosomes and Liquid Biopsies Europe 2018 in Rotterdam, The NetherlandsRotterdam, The

Recent studies have revealed a novel biomolecule, the exosome, which supports cancer metastasis and many other cancer–associated events. Exosomes are a subset of extracellular vesicles (EVs), which are lipid bilayer vesicles secreted from cells. Exosomes have a diameter of 50–150 nm, and they transfer miRNA, mRNA, DNA, and proteins to other cells, thereby mediating intercellular communications. Application of these EVs for biomarker analysis, biofunctions and cell-free regeneration medicine are actively studied, however, common methods for EVs isolation is not always accurately conducted. Especially, EVs represent an important source of potential biomarkers in many diseases that could provide a non-invasive method of early diagnosis or prognosis. Here we will discuss on our current progress on EVs detection as ExoScreen method (Yoshioka et al., Nat Commun, 2014) and usage for early detection of colorectal and pancreatic cancer with high sensitivity and specificity.

Add to Calendar ▼2018-10-24 00:00:002018-10-26 00:00:00Europe/LondonExosomes and Liquid Biopsies Europe 2018Exosomes and Liquid Biopsies Europe 2018 in Rotterdam, The NetherlandsRotterdam, The