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SELECTBIO Conferences Exosomes & Liquid Biopsies Europe 2018

Fred Kramer's Biography



Fred Kramer, Professor of Microbiology, Biochemistry & Molecular Genetics, New Jersey Medical School Rutgers University

Fred Russell Kramer is Professor of Microbiology, Biochemistry, and Molecular Genetics at Rutgers University. After receiving a doctorate from the Rockefeller University, he was a member of the faculty of Columbia University for 17 years, and then moved his laboratory to the Public Health Research Institute, where he has carried out research with his colleagues for the past 28 years.

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Breakfast Lecture: Multiplex Real-Time PCR Assays that Assess the Abundance of Rare Somatic Mutations Associated with Cancer

Thursday, 25 October 2018 at 08:00

Add to Calendar ▼2018-10-25 08:00:002018-10-25 09:00:00Europe/LondonBreakfast Lecture: Multiplex Real-Time PCR Assays that Assess the Abundance of Rare Somatic Mutations Associated with CancerExosomes and Liquid Biopsies Europe 2018 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com

“SuperSelective” PCR primers, due to their unique design, exponentially amplify rare mutant DNA fragments present in a sample, while ignoring abundant related wild-type DNA fragments, even if the only difference between the mutant and the wild-type is a single-nucleotide polymorphism.  Different target mutations whose presence suggests the same therapeutic action can be detected with molecular beacons bearing the same colored fluorophore.  Differently colored molecular beacons are simultaneously present in these assays to determine which therapeutic action should be taken and which therapeutic action should be discontinued.  These multiplex, homogeneous assays are sensitive, rapid, inexpensive, utilize existing PCR instruments, and can be carried out frequently during the course of treatment utilizing non-invasive liquid biopsy samples.


Add to Calendar ▼2018-10-24 00:00:002018-10-26 00:00:00Europe/LondonExosomes and Liquid Biopsies Europe 2018Exosomes and Liquid Biopsies Europe 2018 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com