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SELECTBIO Conferences Point-of-Care Diagnostics, Global Health & Biosensors 2019

Jonathan D Posner's Biography

Jonathan D Posner, Professor of Mechanical Engineering & Chemical Engineering, University of Washington

Jonathan D. Posner is a professor joint in Mechanical Engineering and Chemical Engineering departments as well as adjunct professor in Family Medicine at University of Washington. He directs UW’s Engineering Innovation in Health program that focuses on developing technical solutions to pressing challenges in health and healthcare. Dr. Posner earned his Ph.D. (2001) degree in Mechanical Engineering at the UC Irvine, was a postdoctoral fellow at the Stanford University, and spent 18 months at the von Karman Institute for Fluid Mechanics. His research group works on diverse set of need-driven research projects including medical devices, point-of-care biochemical diagnostics, improved cookstoves for the developing world, and helmets that reduce the risk of concussion. He has 16 patents and patent applications and has founded two companies: VICIS focused on a football helmet that reduces the risk of concussion, and Phoresa focused on point-of-care diagnostics. Dr. Posner is a recipient of UW School of Medicine 2016 Inventor of the Year Award, the National Science Foundation CAREER Award, and recognized for his excellence in experimental research by the von Karman Institute for Fluid Dynamics in Belgium.

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Development of an HIV-1 Viral Load POC Test

Tuesday, 8 October 2019 at 15:00

Add to Calendar ▼2019-10-08 15:00:002019-10-08 16:00:00Europe/LondonDevelopment of an HIV-1 Viral Load POC TestPoint-of-Care Diagnostics, Global Health and Biosensors 2019 in Coronado Island, CaliforniaCoronado Island,

The HIV/AIDS epidemic continues to be a major global health challenge, and accurate, affordable HIV-1 viral load testing is increasingly needed at the point-of-care (POC). Nucleic acid amplification tests (NAATs) provide high diagnostic accuracy of infectious diseases, yet most systems are restricted to central laboratories due to assay and instrumentation complexity. Here we describe a paper membrane based NAAT with integrated sample preparation and amplification using isotachophoresis and recombinase polymerase amplification.  This approach has the potential to reduce the cost and complexity of point-of-care (POC) NAATs. We demonstrate the detection of HIV-1 nucleic acids in whole blood. Preliminary data demonstrate linearity at low copy number which may provide valuable quantitative data on the HIV viral load of a patient.

Add to Calendar ▼2019-10-07 00:00:002019-10-09 00:00:00Europe/LondonPoint-of-Care Diagnostics, Global Health and Biosensors 2019Point-of-Care Diagnostics, Global Health and Biosensors 2019 in Coronado Island, CaliforniaCoronado Island,