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SELECTBIO Conferences Lab-on-a-Chip and Microfluidics Asia 2023

Amy Shen's Biography

Amy Shen, Professor and Provost, Okinawa Institute of Science and Technology Graduate University

Amy Shen is the provost and professor at Okinawa Institute of Science and Technology Graduate University (OIST) in Japan, leading the Micro/Bio/Nanofluidics Unit. Amy's research is focused on microfluidics and lab-on-a-chip devices at the bio/nano-interface, with applications in biotechnology. She is a Fellow of the American Physical Society, the Royal Society of Chemistry, and Society of Rheology. Amy was also a Fulbright Scholar in 2013. She is an associate editor for Soft Matter and serves on the editorial advisory board for ACS Sensors, Journal of Rheology, and Physics of Fluids.

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New Opportunities to Detect Disease and Probe Microbials Using Lab-on-a-Chip Devices

Thursday, 5 October 2023 at 15:00

Add to Calendar ▼2023-10-05 15:00:002023-10-05 16:00:00Europe/LondonNew Opportunities to Detect Disease and Probe Microbials Using Lab-on-a-Chip DevicesLab-on-a-Chip and Microfluidics Asia 2023 in Tokyo, JapanTokyo,

Microfluidics and lab-on-a-chip devices have emerged as powerful platforms to manipulate fluids at small length-scales and open up new possibilities in biophysics and biotechnology research. In this talk, I will showcase two examples of using microfluidics for microbial population research and disease diagnosis.

  • A microfluidic device with controlled microenvironment is developed to study population genetics: many microbial populations proliferate in small channels. In such environments, reproducing cells organize in parallel lanes. Reproducing cells shift these lanes, potentially expelling other cells from the channel. We combine theory and experiments to understand how these dynamics affects the diversity of a microbial population.
  • The rapid transmission and resilience of COVID-19 have led to urgent demands in monitoring humoral response for effective vaccine development, thus a multiplex co-detection platform to discriminate infection-induced from vaccine-induced antibodies is needed. A duplex electrochemical immunosensor for co-detection of anti-nucleocapsid IgG (N-IgG) and anti-spike IgG (S-IgG) is developed by using a two-working electrode system, via an indirect immunoassay, with antibody quantification obtained by differential pulse voltammetry. This duplex immunosensor is then integrated in a microfluidic device to obtain significantly reduced detection time < 7 min) while maintaining its analytical performance. Our duplex microfluidic immunosensor can be easily expanded into multiplex format to achieve high throughput screening for the sero-surveillance of SARS-CoV-2 and other infectious diseases.

Add to Calendar ▼2023-10-05 00:00:002023-10-06 00:00:00Europe/LondonLab-on-a-Chip and Microfluidics Asia 2023Lab-on-a-Chip and Microfluidics Asia 2023 in Tokyo, JapanTokyo,