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SELECTBIO Conferences Single Cell Analysis Summit 2018

John Nolan's Biography

John Nolan, Professor, The Scintillon Institute

John Nolan is a Professor at The Scintillon Institute, where his research group develops and applies new technologies for cytometry. Current projects in his lab include spectral flow cytometry, single particle analysis of natural and synthetic nanoparticles, and surface enhanced Raman scattering (SERS) in cytometry. He is on the Editorial Boards of Cytometry and Current Protocols in Cytometry, a Fellow of the American Institute of Medical and Biological Engineering (AIMBE), and Past-president of the International Society for Advancement of Cytometry (ISAC).

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Single Vesicle Analysis: Making Sense of Exosome Diversity

Tuesday, 2 October 2018 at 09:00

Add to Calendar ▼2018-10-02 09:00:002018-10-02 10:00:00Europe/LondonSingle Vesicle Analysis: Making Sense of Exosome DiversitySingle Cell Analysis Summit 2018 in Coronado Island, CaliforniaCoronado Island,

Extracellular vesicles (EVs) are released by all cells and carry molecular cargo that can be delivered to nearby and distant cells to affect their function. Biofluids such as plasma contain EVs from many different cell types, and thus represent a rich source of potential biomarkers for liquid biopsy and other applications. However, progress towards this potential is slowed by the small size and heterogeneous nature of EVs found in various biofluids. We have been developing high resolution analysis methods to measure and characterize individual EV and classes of UVs to better understand their cellular source, molecular cargo, and potential destinations and functional effects. These methods includes optimized dye formulations, antibodies, and calibrators and standards needed for inter-lab comparisons. In this presentation I will highlight the potential roles of EV in biology, the challenges for their measurement, and new insights into the diversity of EVs revealed by new high resolution analysis methods.

Add to Calendar ▼2018-10-02 00:00:002018-10-03 00:00:00Europe/LondonSingle Cell Analysis Summit 2018Single Cell Analysis Summit 2018 in Coronado Island, CaliforniaCoronado Island,