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SELECTBIO Conferences Single Cell Analysis Summit 2018

Lydia Sohn's Biography

Lydia Sohn, Professor, Department of Mechanical Engineering, University of California, Berkeley

Lydia L. Sohn received her A.B. (Chemistry and Physics, 1988), M.S. (Physics, 1990), and Ph.D. (Physics, 1992) from Harvard University. She was an NSF/NATO postdoc at Delft University of Technology and a postdoc at AT&T Bell Laboratories (1993-1995). Sohn was an Assistant Professor of Physics at Princeton University prior to joining the Mechanical Engineering Dept. at UC Berkeley in 20013. Her work focuses on developing quantitative techniques to probe single cells. Sohn has received numerous awards including the NSF CAREER, Army of Research Young Investigator Award, DuPont Young Professor Award, and a Bakar Fellowship. In 2014, she was one of five winners in the “Identifying Platform Technologies for Advancing Life Sciences Research” competition for her work on Node-Pore Sensing. Most recently, she was elected a Fellow of the American Institute for Medical and Biological Engineering.

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A Platform for Detecting Tumor-Derived Exosomes

Tuesday, 2 October 2018 at 09:30

Add to Calendar ▼2018-10-02 09:30:002018-10-02 10:30:00Europe/LondonA Platform for Detecting Tumor-Derived ExosomesSingle Cell Analysis Summit 2018 in Coronado Island, CaliforniaCoronado Island,

Late-stage lung-cancer diagnosis is the major contributor to the poor survival of lung cancer patients. The lack of symptoms specific to early-stage lung cancer and the low sensitivity and high cost of current screening methods, are current barriers to early diagnosis. To address this challenge and enable rapid, cost-effective lung cancer screening, we are developing a microfluidic platform to detect tumor-derived exosomes in saliva. Our detection method utilizes resistive-pulse sensing to measure the size change of a micron-sized antibody-coated colloid when tumor-derived exosomes bind to it. Microscale in size, our platform can easily be manufactured using standard lithographic techniques. In this talk, I will describe our platform and the results we have achieved thus far to demonstrate its utility toward detecting tumor-derived exosomes for earl-stage detection of lung cancer.

Add to Calendar ▼2018-10-02 00:00:002018-10-03 00:00:00Europe/LondonSingle Cell Analysis Summit 2018Single Cell Analysis Summit 2018 in Coronado Island, CaliforniaCoronado Island,