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SELECTBIO Conferences 3D-Printing in the Life Sciences

Ruogang Zhao's Biography

Ruogang Zhao, Associate Professor, SUNY Buffalo

Dr. Ruogang Zhao is an Associate Professor in the Department of Biomedical Engineering at the State University of New York at Buffalo. He received his PhD in biomaterials and biomedical engineering from the University of Toronto. He was a postdoctoral fellow in biological physics at the Johns Hopkins University before moving to Buffalo. Through combining advanced biofabrication technologies and biomechanics, he has developed a unique research program to address the unmet need to model the physiology and pathology of mechanosensitive tissues. He has received several awards including the Heart and Stroke Foundation of Canada Doctoral Research Award in 2011, the 2019 Young Innovators Award of Cellular and Molecular Bioengineering and the Outstanding Abstract Award from the Society of Biomaterials in 2019.

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Ultrafast 3D Printing of Large-scale Engineered Tissues

Tuesday, 15 October 2019 at 10:00

Add to Calendar ▼2019-10-15 10:00:002019-10-15 11:00:00Europe/LondonUltrafast 3D Printing of Large-scale Engineered Tissues3D-Printing in the Life Sciences in Coronado Island, CaliforniaCoronado Island,

Large size engineered soft tissues hold great promise for tissue repair and organ transplantation, but their fabrication using 3D bioprinting is hindered by the cellular damage caused by the prolonged exposure to the unfavorable printing environment and the limited multiscale printing capability. Here we present a Fast hydrogeL prOjection stereolithogrAphy Technology (FLOAT) that can create a centimeter-sized, multiscale solid hydrogel tissue model within several minutes, thus significantly reducing environmental stress-induced cellular injuries. As a proof of principle, we rapidly print a centimeter-sized hydrogel liver model containing perfusable vascular channels. Media perfusion enabled by the channel network is shown to play a critical role in promoting cell survival and metabolic function in the deep core of the model over long term. We demonstrate the good compatibility of the FLOAT with multiple photocurable hydrogel materials and the strategies to optimize the printing material to improve tissue regeneration such as endothelialization of pre-fabricated vascular channels. Together, these studies show that FLOAT is a promising approach for the fabrication of vascularized engineered tissues of clinically-relevant size and potentially suitable for rapid injury repair and transplantation.

Add to Calendar ▼2019-10-14 00:00:002019-10-15 00:00:00Europe/London3D-Printing in the Life Sciences3D-Printing in the Life Sciences in Coronado Island, CaliforniaCoronado Island,