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SELECTBIO Conferences Point-of-Care Diagnostics, Global Health & Biosensors 2019

Chong Ahn's Biography

Chong Ahn, Distinguished University Research Professor, Mitchell P. Kartalia Chair Professor of BioMEMS, University of Cincinnati

Dr Ahn is Distinguished University Research Professor and Mitchell P. Kartalia Endowed Chair Professor of BioMEMS in the Department of Electrical Engineering and Computer Science at the University of Cincinnati. He is currently Director of the Engineering Research Center (ERC) Clean Room and Ohio Center for Microfluidic Innovation (OCMI) at the University of Cincinnati. He has been recognized internationally as one of the pioneers in the Biosensors, BioMEMS, Microfluidics, Lab-on-a-Chips, and Point-of-Care Testing (POCT) clinical diagnostic fields. His research interests include the design, simulation, fabrication and characterization of BioMEMS devices, microfluidic device and systems, biosensors and biochips, lab-on-a-chips, in vitro diagnostics (IVD), and point-of-care testing clinical diagnostics or neurosurgical monitoring. He has published over ~350 journal and peer-reviewed conference proceeding papers, and chaired numerous international conferences and steering committees. He was invited as a plenary or keynote speaker from the prestigious international conferences such as uTAS, Eurosensors, APCOT, or IEEE IEDM. He served as one of the Scientific Advisory Board members of the Bill & Melinda Gates Foundation on microfluidics and point-of-care testing diagnostics in 2016.

He has 12 issued US patents. He was the founder of Siloam Biosciences Inc. (which was acquired by Mico BioMed Inc.) in Cincinnati, Ohio, USA. He was the awardees of the University of Cincinnati’s Emerging Entrepreneur Award (2009) and Established Entrepreneur Award (2011). He received Alice Hamilton Award for Excellence in Occupational Safety and Health Research from CDC-NIOSH in 2020, and received the Best Journal Paper Award of the IEEE Sensors Journal in 2009. He currently serve as an Editor of the IEEE/ASME Journal of Microelectromechanical Systems (JMEMS), Editorial Boards of Micro and Nano Systems Letters and Biochip Journal, Editorial Advisory Board of the Journal of Microfluidics and Nanofluidics, and previously served as the Editorial Boards of the Journal of Micromechanics and Microengineering (JMM), IEEE Sensors Journal, and Small.

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A New Lab-on-a-Chip (LOC) Platform with On-Chip Reservoirs of Liquid Reagents for POCT Applications

Tuesday, 8 October 2019 at 14:00

Add to Calendar ▼2019-10-08 14:00:002019-10-08 15:00:00Europe/LondonA New Lab-on-a-Chip (LOC) Platform with On-Chip Reservoirs of Liquid Reagents for POCT ApplicationsPoint-of-Care Diagnostics, Global Health and Biosensors 2019 in Coronado Island, CaliforniaCoronado Island,

A new lab-on-a-chip (LOC) platform with on-chip liquid reservoirs holding all reagents for high-sensitive immunoassay has been designed, developed and characterized for Tumor Necrosis Factor - alpha (TNF-alpha), a protein biomarker that is caused by lung inflammations or cancers. The designed LOC device is composed of four reservoirs for sample, enzyme conjugated detection antibody, wash buffer and chemiluminescence substrate in liquid form, along with spiral reacting microchannels coated with capture antibody. All reservoirs and spiral microchannels were connected in series and designed to perform sequential delivery of immunoassay reagents with minimal user intervention.  The developed LOC measured TNF-a concentration as low as 16 pg/mL in plasma sample from rats and also had a limit of detection (LOD) of 0.5 pg/mL in spiked artificial plasma. The detected range of TNF-a is low enough to diagnose early responses to lung inflammation or cancers in humans. In addition, the analysis time was drastically reduced, to about 30 minutes as opposed to hours in conventional assay methods. Successful implementation of a high-sensitive, chemiluminescence based immunoassay on a pre-loaded LOC, as reported in this work, can pave the way towards developing a new POCT testing platform.

Add to Calendar ▼2019-10-07 00:00:002019-10-09 00:00:00Europe/LondonPoint-of-Care Diagnostics, Global Health and Biosensors 2019Point-of-Care Diagnostics, Global Health and Biosensors 2019 in Coronado Island, CaliforniaCoronado Island,