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SELECTBIO Conferences Lab-on-a-Chip and Microfluidics World Congress 2018

Shoji Takeuchi's Biography

Shoji Takeuchi, Professor, Center For International Research on Integrative Biomedical Systems (CIBiS), Institute of Industrial Science, The University of Tokyo

Shoji Takeuchi received the B.E, M.E., and Dr. Eng. degrees in mechanical engineering from the University of Tokyo, Tokyo, Japan, in 1995, 1997, and 2000, respectively. He is currently a Professor in the Center for International Research on Integrative Biomedical Systems (CIBiS), Institute of Industrial Science (IIS), University of Tokyo. Since 2008, he is a director of Collaborative Research Center for Bio/Nano Hybrid Process at IIS. His current research interests include membrane protein chips, bottom-up tissue engineering and biohybrid MEMS. He received several awards including Young Scientists' Prize, the Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology in 2008, the JSPS prize from the Japan Society for the Promotion of Science in 2010.

Shoji Takeuchi Image

Microfluidics For Biohybrid Devices

Wednesday, 3 October 2018 at 16:00

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In this presentation, I will talk about several approaches to develop MEMS/Microfluidic devices combined with living materials for various biomedical sensing and healthcare applications. Living materials show superior functions to the artificial ones such in terms of the ability to recognize/produce biomolecules. For example, membrane proteins achieve highly-sensitive and selective detection of several chemicals at the molecular level; they can even distinguish between different chemical moieties found in various odorants. When a certain ion channel activating a single ligand molecule opens for 1 s under a 100 mV-membrane potential, the number of monovalent ions that are transferred through the ion channel reaches the 106-107 level and generates a few pico-amperes. This reaction means that chemical signals are converted to amplified current signals in living systems; the system can be regarded as a transistor with an excellent amplifier. Here, one of my talk will include our approaches toward biohybrid sensors: a microdevice having membrane proteins (receptors) reconstituted into cells or planar lipid bilayers. We believe that the devices are useful for a highly-selective and rapid detection of various chemicals including drugs, odorants and tastants. This approach is likely to lead to a wide variety of applications including environmental monitoring, food control, and highly-sensitive diagnostic tools.

Add to Calendar ▼2018-10-01 00:00:002018-10-03 00:00:00Europe/LondonLab-on-a-Chip and Microfluidics World Congress 2018Lab-on-a-Chip and Microfluidics World Congress 2018 in Coronado Island, CaliforniaCoronado Island,