Shopping Cart (0)
My Account

Shopping Cart
SELECTBIO Conferences Structural & Computational Chemistry

Sander Nabuurs's Biography

Sander Nabuurs, Head Molecular Modelling and Computational Chemistry, Lead Pharma

Dr. Sander Nabuurs is currently responsible for the structural bioinformatics and computational chemistry efforts at the young pharmaceutical company Lead Pharma, which aims to develop novel therapeutics against ageing related diseases.
Prior to his appointment at Lead Pharma, he was a group leader in Computational Drug Discovery at the Centre for Molecular and Biomolecular Informatics of the Radboud University Nijmegen Medical Centre and worked for several years at the pharmaceutical company Organon / Schering-Plough in the department of Molecular Design and Informatics.
Sander holds an MSc in biophysical chemistry and a PhD in structural bioinformatics.

Sander Nabuurs Image

Approaches to Address Protein Flexibility in Molecular Docking

Wednesday, 14 March 2012 at 09:30

Add to Calendar ▼2012-03-14 09:30:002012-03-14 10:30:00Europe/LondonApproaches to Address Protein Flexibility in Molecular Docking

An important but complex aspect of structure-based drug design is accurately modelling receptor flexibility. This contribution will focus on different approaches we have developed to address protein flexibility in modelling protein-ligand complexes. This ranges from the prediction of binding site plasticity to the improved ranking and scoring of induced fit docking solution utilizing protein structure validation techniques.

Add to Calendar ▼2012-03-13 00:00:002012-03-14 00:00:00Europe/LondonStructural and Computational