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SELECTBIO Conferences Circulating Biomarkers World Congress 2020

Susanne Gabrielsson's Biography

Susanne Gabrielsson, Professor, Division of Immunology and Allergy, Department of Medicine Solna, Karolinska Institutet

Professor Gabrielsson is leading a group dedicated to exosome/extracellular vesicle research at the Karolinska Institutet, Sweden. She has been a pioneer in the fields of exosomes in lung diseases and the immune effects of exosomes. Dr. Gabrielsson was the first to describe the presence of exosomes in bronchoalveolar lavage fluid, and in breast milk. Her work has revealed that exosomes are major players in lung diseases such as asthma and sarcoidosis. Her work in animal models is giving new insights into how exosome-based cancer immunotherapeutics should be designed for optimal immune stimulation.

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Optimizing Dendritic Cell-Derived Exosomes For Cancer Immunotherapy

Monday, 17 February 2020 at 12:15

Add to Calendar ▼2020-02-17 12:15:002020-02-17 13:15:00Europe/LondonOptimizing Dendritic Cell-Derived Exosomes For Cancer ImmunotherapyCirculating Biomarkers World Congress 2020 in Coronado Island, CaliforniaCoronado Island,

Peptide loaded exosomes are promising cancer treatment vehicles, however, low T cell responses in human clinical trials indicate a need to further understand exosome-induced immunity. We previously demonstrated that antigen-loaded exosomes carry whole protein antigens and require B cells for induction of antigen-specific T cells. I will discuss our latest data where we investigated the need for different immune related molecules on exosomes to induce T cell responses and tumor rejection in the B16 mouse melanoma model. Our data demonstrate ways to increase the feasibility of exosome-based therapeutic approaches in cancer.

Add to Calendar ▼2020-02-17 00:00:002020-02-18 00:00:00Europe/LondonCirculating Biomarkers World Congress 2020Circulating Biomarkers World Congress 2020 in Coronado Island, CaliforniaCoronado Island,